The MET/HGFR Antibody from MyBioSource.com is a Mouse Monoclonal antibody to MET. This antibody recognizes Human, and Mouse antigen. The MET/HGFR Antibody has been validated for the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene